Molecular identification of Corynebacterium pseudotuberculosis in sheep

An improved Corynebacterium pseudotuberculosis vaccine for sheep.

Extensive experiments in mice confirmed that the immunogenicity of a Corynebacterium pseudotuberculosis vaccine could not be significantly improved with the use of various adjuvants. Immunity against C. pseudotuberculosis likewise could not be enhanced by incorporating various immunostimulants into the vaccine or by the use of live vaccines. However, a combination of aluminium hydroxide gel and...

Identification of a novel antigen from Corynebacterium pseudotuberculosis that protects sheep against caseous lymphadenitis.

A 40-kDa protein antigen from Corynebacterium pseudotuberculosis has been identified by application of a strategy that employs locally derived antibody-secreting cells (ASC). ASC probes generated by culture of ASC obtained from the lymph node draining the site of infection showed a specificity restricted to a 40-kDa antigen. Analysis of immunoblots with sequential serum samples taken from sheep...

Isolation of Corynebacterium pseudotuberculosis from Camel in Iran

Identification of the protective and toxic antigens of Corynebacterium pseudotuberculosis.

Cameron (1964) showed that the immunizing property of Corynebacterium pseudotuberculosis cells was closely associated with the toxicity of cell endoplasm and the ability of formalin-killed cells to produce sterile abscesses. He also found that the presence of toxic factors in the cells depended on the culture medium to a large extent. Furthermore Cameron & Swart (1965) developed a fluid medium ...

Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis—General Aspects

V. A. de. C. Azevedo Departmento de Biologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil Abstract Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis are potentially diphtheria toxin-producing microorganisms related to different infectious processes involving both human and animal hosts. This chapte...